Versetel™ Polypropylene Fumarate (PPF) Resorbable Resins
While the use of 3D printing has shown explosive growth in industries ranging from automotive to personal care industries, the deployment of true 3D fabrication methods in the biomedical implant space has lagged, driven by the lack of medically acceptable resorbable resins.
A resorbable polymer that has attracted much interest as an optically 3D printable resin for biomedical use is polypropylene fumarate (PPF). First developed almost thirty years ago, PPF has long been recognized as a resorbable material of potential broad utility and which can be printed using photocrosslinking 3D printing. Its availability has been hampered by an inability to synthesize PPF commercially or to cGMP standards.
21MedTech has an exclusive patent license on a novel process to produce PPF with tight control of chemical and mechanical properties and that is appropriate for high levels of production under cGMP conditions. The unique material process enables 21MedTech to prepare Versetel PPF as a fluid or solid, allowing great flexibility in processing materials to the demands of new surgical techniques. The production of Versetel PPF is highly reproducible.
The ability to 3D print this material that includes photo crosslinking opens tissue engineering and device fabrication to a wide range of opportunities. We can control precise geometries, porosity, degradation, and functionalities of Versetel PPF resins.
Key properties of VERSETEL PPF include:
- Best-in-class 3D photo crosslinkable resin
- Liquid at room temperature
- Provides scaffold for bone or soft tissue growth
- Can adjust absorption from 1 to 9 months
- Can provide short or long-term drug release
- Clinical applications include orthopedic, trauma, soft tissue, mesh, drug delivery, vascular, tissue engineering and 3D manufacturing including photocrosslinking bioresorbable